| System Information |
| StepperID | DES_01 |
| Name | matrix |
| Variable List |
| ID | Name | Value |
| SIZE | ----- | 0.43e-15 |
| CS | Citrate synthase | 100 |
| ACO | Aconitase | 100 |
| IDHa | Isocitrate dehydrogenase NAD_p | 100 |
| IDHb | Isocitrate dehydrogenase NADP_p | 100 |
| OGDC | Oxoglutarate dehydrogenase complex | 100 |
| SCS | Succinyl-CoA synthetase | 100 |
| FM | Fumarase | 100 |
| MDH | Malate dehydrogenase | 100 |
| AlaTA | Alanine transaminase | 100 |
| AspTA | Aspartate transaminase | 100 |
| NDK | Nucleoside Diphosphate Kinase | 100 |
| PDC | Pyruvate dehydrogenase complex | 100 |
| PC | Pyruvate carboxylase | 100 |
| ATP | ATP | 179.708411703224 |
| ADP | ADP | 121948 |
| GTP | GTP | 2579.20277507972 |
| GDP | GDP | 1338851.79722492 |
| Pi | Pi | 2507394.57819516 |
| Cit | Citrate | 583454.667302838 |
| IsoCit | Isocitrate | 74758.078233458 |
| OG | Oxoglutarate | 424.208338797423 |
| SCoA | Succinyl-CoA | 32.4504402506517 |
| Suc | Succinate | 1132.50269451216 |
| Fum | Fumarate | 231566.703717434 |
| Mal | Malate | 1028383.06170441 |
| OXA | Oxaloacetate | 301.821669042799 |
| Asp | Aspartate | 244090.279722199 |
| Glu | Glutamate | 801482.170624405 |
| Ala | Alanine | 1016708.5496534 |
| Pyr | Pyruvate | 27777 |
| CoA | CoA | 285.731270996556 |
| Acetyl_CoA | Acetyl-CoA | 104498.130355066 |
| NADH | NADH | 3671.57931748813 |
| NAD_p | NADH | 61909.4206825119 |
| NADP_p | NADP+ | 58072.7464491537 |
| NADPH | NADPH | 7508.25355084638 |
| CO2 | CO2 | 42631670.6915103 |
| Car | Carnitine | 47417.8343327729 |
| PalCar | L-Palmitoylcarnitine | 213280.165667227 |
| ETFred | ETFred | 82.3098404642309 |
| ETFox | ETFox | 88.6901595357691 |
| c16Acyl_CoA | Hexadecanoyl-CoA | 330.827026222392 |
| c16Enoyl_CoA | trans-Hexadec-2-enoyl-CoA | 698.259337411322 |
| c16Hydroxyacyl_CoA | S-3-Hydroxyhexadecanoyl-CoA | 2.6986210319787 |
| c16Oxoacyl_CoA | 3-Oxohexadecanoyl-CoA | 769.422298088143 |
| c14Acyl_CoA | Tetradecanoyl-CoA | 330.617485647672 |
| c14Enoyl_CoA | trans-Tetradec-2-enoyl-CoA | 698.509729746527 |
| c14Hydroxyacyl_CoA | S-3-Hydroxytetradecanoyl-CoA | 2.58048651753345 |
| c14Oxoacyl_CoA | 3-Oxotetradecanoyl-CoA | 770.643049235415 |
| c12Acyl_CoA | Dodecanoyl-CoA | 330.206115962825 |
| c12Enoyl_CoA | trans-Dodec-2-enoyl-CoA | 699.861060725284 |
| c12Hydroxyacyl_CoA | S-3-Hydroxydodecanoyl-CoA | 2.07477407638552 |
| c12Oxoacyl_CoA | 3-Oxododecanoyl-CoA | 763.336129328169 |
| c10Acyl_CoA | Decanoyl-CoA | 330.576253941254 |
| c10Enoyl_CoA | trans-Dec-2-enoyl-CoA | 700.435268610825 |
| c10Hydroxyacyl_CoA | S-3-Hydroxydecanoyl-CoA | 2.47334811965372 |
| c10Oxoacyl_CoA | 3-Oxodecanoyl-CoA | 762.161407615672 |
| c8Acyl_CoA | Octanoyl-CoA | 331.678904096009 |
| c8Enoyl_CoA | trans-Oct-2-enoyl-CoA | 700.66830851517 |
| c8Hydroxyacyl_CoA | S-3-Hydroxyoctanoyl-CoA | 2.27437977305555 |
| c8Oxoacyl_CoA | 3-Oxooctanoyl-CoA | 762.939438852062 |
| c6Acyl_CoA | Hexanoyl-CoA | 331.857436122862 |
| c6Enoyl_CoA | trans-Hex-2-enoyl-CoA | 700.684311272332 |
| c6Hydroxyacyl_CoA | S-3-Hydroxyhexanoyl-CoA | 2.59281375270886 |
| c6Oxoacyl_CoA | 3-Oxohexanoyl-CoA | 763.92453277689 |
| c4Acyl_CoA | Butanoyl-CoA | 331.206626429918 |
| c4Enoyl_CoA | trans-But-2-enoyl-CoA | 701.958315797018 |
| c4Hydroxyacyl_CoA | S-3-Hydroxybutanoyl-CoA | 2.02452499607275 |
| Acetoacetyl_CoA | Acetoacetyl-CoA | 239686.195949022 |
| H_p | H+:MATRIX | 3 |
| Process List |
| Process Class/ID | Properties |
RandomBiBiFluxProcess
CS
|
| ID | CS |
| Name | Citrate synthase |
| k1 | 6.8E10 |
| k_1 | 8.1E8 |
| k2 | 3.0E10 |
| k_2 | 7.2E8 |
| k3 | 6.2E10 |
| k_3 | 5.1E8 |
| k4 | 1.2E10 |
| k_4 | 4.0E8 |
| k5 | 1.4E9 |
| k_5 | 2.4E8 |
| k6 | 4.1E10 |
| k_6 | 1.1E8 |
| k7 | 5E10 |
| k_7 | 9.8E8 |
| k8 | 5.3E10 |
| k_8 | 7.7E8 |
| VariableReferenceList |
S0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:OXA | -1 |
S1 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:Acetyl_CoA | -1 |
P0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:Cit | 1 |
P1 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:CoA | 1 |
C0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:CS | 0 |
MichaelisUniUniReversible1Process
ACO
|
| ID | ACO |
| Name | Aconitase |
| Ks | 0.50E-3 |
| Kp | 0.11E-3 |
| KcF | 20.47 |
| KcR | 31.44 |
| VariableReferenceList |
S0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:Cit | -1 |
P0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:IsoCit | 1 |
C0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:ACO | 0 |
IDHaProcess
IDHa
|
| ID | IDHa |
| Name | Isocitrate dehydrogenase NAD+ |
| KcF | 105 |
| b | 29.6 |
| c | 0.00023 |
| d | 7.8e-05 |
| e | 0.00064 |
| f | 0.00036 |
| VariableReferenceList |
S0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:IsoCit | -1 |
S1 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:NAD_p | -1 |
P0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:OG | 1 |
P1 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:NADH | 1 |
P2 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:CO2 | 1 |
P3 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:H_p | 1 |
E0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:ADP | 0 |
C0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:IDHa | 0 |
IDHbProcess
IDHb
|
| ID | IDHb |
| Name | Isocitrate dehydrogenase NADP+ |
| phi0 | 5.1E-2 |
| phi1 | 9.5E-8 |
| phi2 | 0.96E-6 |
| phi12 | 9E-8 |
| phir0 | 6.6E-2 |
| phir1 | 0.37E-6 |
| phir2 | 29E-6 |
| phir3 | 2.5E-4 |
| phir12 | 6E-12 |
| phir13 | 1.3E-10 |
| phir23 | 9.4E-8 |
| phir123 | 4.6E-14 |
| VariableReferenceList |
S0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:IsoCit | -1 |
S1 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:NADP_p | -1 |
P0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:OG | 1 |
P1 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:NADPH | 1 |
P2 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:CO2 | 1 |
P3 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:H_p | 1 |
C0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:IDHb | 0 |
MultisitePingPongProcess
OGDC
|
| ID | OGDC |
| Name | Oxoglutarate Dehydrogenase Complex |
| KmA | 0.22E-3 |
| KmB | 0.025E-3 |
| KmC | 0.050E-3 |
| KmP | 3E-4 |
| KmR | 6E-4 |
| Kia | 7.2E-4 |
| Kib | 7.4E-4 |
| Kic | 1E-4 |
| Kip | 1.1E-6 |
| Kiq | 81E-6 |
| Kir | 25E-6 |
| KcF | 177 |
| VariableReferenceList |
S0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:OG | -1 |
S1 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:CoA | -1 |
S2 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:NAD_p | -1 |
P0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:CO2 | 1 |
P1 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:SCoA | 1 |
P2 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:NADH | 1 |
P3 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:H_p | 1 |
C0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:OGDC | 0 |
SCSProcess
SCS
|
| ID | SCS |
| Name | Succinyl-CoA synthetase |
| KmA | 5E-6 |
| KmB | 3.5E-5 |
| KmC | 4.5E-4 |
| KmP | 6E-4 |
| KmQ | 7.5E-6 |
| KmC2 | 4.5E-4 |
| KmP2 | 6E-4 |
| Keq | 8.375 |
| Kia | 4E-4 |
| Kib | 2E-5 |
| Kic | 3E-5 |
| Kip | 7E-2 |
| Kiq | 5E-6 |
| Kir | 6.7E-6 |
| Kc1 | 100 |
| Kc2 | 100 |
| VariableReferenceList |
S0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:GDP | -1 |
S1 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:SCoA | -1 |
S2 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:Pi | -1 |
P0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:Suc | 1 |
P1 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:GTP | 1 |
P2 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:CoA | 1 |
C0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:SCS | 0 |
MichaelisUniUniReversible1Process
FM
|
| ID | FM |
| Name | Fumarase |
| Kp | 2.5E-5 |
| Ks | 0.5E-5 |
| KcF | 800 |
| KcR | 900 |
| VariableReferenceList |
S0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:Fum | -1 |
P0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:Mal | 1 |
C0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:FM | 0 |
CBOrderedBiBiProcess
MDH
|
| ID | MDH |
| Name | Malate Dehydrogenase |
| KmS1 | 72E-6 |
| KmS2 | 110E-6 |
| KmP1 | 1600E-6 |
| KmP2 | 170E-6 |
| KiS1 | 11E-6 |
| KiS2 | 100E-6 |
| KiP1 | 7100E-6 |
| KiP2 | 1900E-6 |
| KcF | 0.396 |
| KcR | 0.040 |
| VariableReferenceList |
S0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:NADH | -1 |
S1 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:OXA | -1 |
S2 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:H_p | -1 |
P0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:Mal | 1 |
P1 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:NAD_p | 1 |
C0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:MDH | 0 |
PingPongBiBiProcess
AlaTA
|
| ID | AlaTA |
| Name | Alanine Transaminase |
| KmS1 | 2E-3 |
| KmS2 | 0.4E-3 |
| KmP1 | 32E-3 |
| KmP2 | 0.4E-3 |
| KiS1 | 8.7E-3 |
| KiP2 | 12E-3 |
| Keq | 0.69 |
| KcF | 337 |
| KcR | 0.15 |
| VariableReferenceList |
S0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:Ala | -1 |
S1 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:OG | -1 |
P0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:Glu | 1 |
P1 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:Pyr | 1 |
C0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:AlaTA | 0 |
PingPongBiBiProcess
AspTA
|
| ID | AspTA |
| Name | Aspartate Transaminase |
| KmS1 | 0.9E-3 |
| KmS2 | 0.1E-3 |
| KmP1 | 0.04E-3 |
| KmP2 | 4E-3 |
| KiS1 | 2E-3 |
| KiP2 | 8.3E-3 |
| Keq | 6.2 |
| KcF | 300 |
| KcR | 1000 |
| VariableReferenceList |
S0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:Asp | -1 |
S1 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:OG | -1 |
P0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:OXA | 1 |
P1 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:Glu | 1 |
C0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:AspTA | 0 |
PingPongBiBiProcess
NDK
|
| ID | NDK |
| Name | Nucleoside Diphosphate Kinase |
| KmS1 | 0.31E-3 |
| KmS2 | 0.043E-3 |
| KmP1 | 0.050E-3 |
| KmP2 | 0.25E-3 |
| KiS1 | 0.21E-3 |
| KiP2 | 0.35E-3 |
| Keq | 1.28 |
| KcF | 6883 |
| KcR | 5950 |
| VariableReferenceList |
S0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:ATP | -1 |
S1 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:GDP | -1 |
P0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:ADP | 1 |
P1 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:GTP | 1 |
C0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:NDK | 0 |
MultisitePingPongProcess
PDC
|
| ID | PDC |
| Name | Pyruvate Dehydrogenase Complex |
| KmA | 25E-6 |
| KmB | 13E-6 |
| KmC | 50E-6 |
| KmP | 5.9E-7 |
| KmR | 6.9E-7 |
| Kia | 5.5E-4 |
| Kib | 3.0E-4 |
| Kic | 1.8E-4 |
| Kip | 6.0E-5 |
| Kiq | 35E-6 |
| Kir | 36E-6 |
| KcF | 856 |
| VariableReferenceList |
S0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:Pyr | -1 |
S1 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:CoA | -1 |
S2 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:NAD_p | -1 |
P0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:CO2 | 1 |
P1 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:Acetyl_CoA | 1 |
P2 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:NADH | 1 |
P3 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:H_p | 1 |
C0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:PDC | 0 |
PCProcess
PC
|
| ID | PC |
| Name | Pyruvate carboxylase |
| KmA | 0.11E-3 |
| KmB | 1.63E-3 |
| KmC | 0.37E-3 |
| KmP | 16E-3 |
| KmQ | 0.24E-3 |
| KmR | 0.051E-3 |
| Keq | 9.0 |
| Kia | 0.15E-3 |
| Kib | 1.6E-3 |
| Kic | 0.13E-3 |
| Kip | 7.9E-3 |
| Kiq | 0.19E-3 |
| Kir | 0.24E-3 |
| KcF | 200 |
| KcR | 20 |
| VariableReferenceList |
S0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:ATP | -1 |
S1 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:CO2 | -1 |
S2 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:Pyr | -1 |
P0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:Pi | 1 |
P1 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:ADP | 1 |
P2 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:OXA | 1 |
C0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:PC | 0 |
| System Information |
| StepperID | DES_01 |
| Name | mt-innermembrane |
| Variable List |
| ID | Name | Value |
| AAC | ATP-ADP Carrier | 1000 |
| AGC | Asp-Glu Carrier | 1000 |
| PiC | Pi Carrier | 1000 |
| PYC | Pyruvate Carrier | 1000 |
| OGC | Oxoglutarate Carrier | 1000 |
| DIC | Dicarboxylate Carrier | 1000 |
| CIC | Citrate Carrier | 1000 |
| SDH | Succinate dehydrogenase | 100 |
| Complex_I | NADH dehydrogenase | 1000 |
| Complex_III | UQ-Cyt c reductase | 3000 |
| Complex_IV | Cytochrome c oxidase | 7000 |
| Complex_V | ATP synthase | 900 |
| CAC | carnitine carrier | 100 |
| CPT_II | CPT II | 100 |
| ACD | Acyl-CoA dehydrogenase | 100 |
| ECH | Enoyl-CoA hydratase | 100 |
| HCD | 3-Hydroxyacyl-CoA dehydrotgenase | 100 |
| OCT | 3-Ketoacyl-CoA thiolase | 100 |
| ETF_QO | ETF-Q oxidoreductase | 100 |
| Process List |
| Process Class/ID | Properties |
AACProcess
AAC_ADPin
|
| ID | AAC_ADPin |
| Name | ATP-ADP Carrier |
| kf0 | 0.9 |
| kr0 | 0.9 |
| normalize | 2.21 |
| Kd1 | 5.9E-4 |
| Kd2 | 5.9E-4 |
| Cf | 3.30 |
| Cr | -3.34 |
| T | 310.0 |
| VariableReferenceList |
S0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MT_IMS:ADP | -1 |
P0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:ADP | 1 |
E0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MT_IMS:H_p | 0 |
E1 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:H_p | 0 |
C0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MT_IM:AAC | 0 |
AACProcess
AAC_ATPex
|
| ID | AAC_ATPex |
| Name | ATP_ADP Carrier |
| kf0 | 1.0 |
| kr0 | 1.0 |
| normalize | 2.21 |
| Kd1 | 5.9E-4 |
| Kd2 | 5.9E-4 |
| Cf | 10.2 |
| Cr | -10.2 |
| T | 310.0 |
| VariableReferenceList |
S0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:ATP | -1 |
P0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MT_IMS:ATP | 1 |
E0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MT_IMS:H_p | 0 |
E1 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:H_p | 0 |
C0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MT_IM:AAC | 0 |
RapidEquilibriumRandomBiBiProcess
AGC
|
| ID | AGC |
| Name | Aspartate Glutamate Carrier |
| KiS1 | 80E-6 |
| KiS2 | 3.2E-3 |
| KiP1 | 180E-6 |
| KiP2 | 2.8E-3 |
| KcF | 10.0 |
| KcR | 10.0 |
| alpha | 1.0 |
| beta | 1.0 |
| gamma | 1.0 |
| delta | 1.0 |
| VariableReferenceList |
S0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MT_IMS:Asp | -1 |
S1 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:Glu | -1 |
P0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MT_IMS:Glu | 1 |
P1 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:Asp | 1 |
C0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MT_IM:AGC | 0 |
RapidEquilibriumRandomBiBiProcess
PYC
|
| ID | PYC |
| Name | Pyruvate Carrier |
| KiS1 | 6.1E-4 |
| KiS2 | 5.9E-4 |
| KiP1 | 2.6E-4 |
| KiP2 | 4.1E-4 |
| KcF | 0.84 |
| KcR | 0.78 |
| alpha | 1.0 |
| beta | 1.0 |
| gamma | 1.0 |
| delta | 1.0 |
| VariableReferenceList |
S0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MT_IMS:Pyr | -1 |
S1 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:H_p | -1 |
P0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MT_IMS:H_p | 1 |
P1 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:Pyr | 1 |
C0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MT_IM:PYC | 0 |
RapidEquilibriumRandomBiBiProcess
PiC
|
| ID | PiC |
| Name | Phosphate Carrier |
| KiS1 | 0.87 |
| KiS2 | 1.86E-08 |
| KiP1 | 32.84E-9 |
| KiP2 | 11.12E-3 |
| KcF | 37.9 |
| KcR | 37.0 |
| alpha | 1.0 |
| beta | 1.0 |
| gamma | 1.0 |
| delta | 1.0 |
| VariableReferenceList |
S0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MT_IMS:Pi | -1 |
S1 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MT_IMS:H_p | -1 |
P0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:H_p | 1 |
P1 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:Pi | 1 |
C0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MT_IM:PiC | 0 |
RapidEquilibriumRandomBiBiProcess
OGC
|
| ID | OGC |
| Name | Oxoglutarate Carrier |
| KiS1 | 0.3E-3 |
| KiS2 | 0.7E-3 |
| KiP1 | 1.4E-3 |
| KiP2 | 0.17E-3 |
| KcF | 3.675 |
| KcR | 4.83 |
| alpha | 1.0 |
| beta | 1.0 |
| gamma | 1.0 |
| delta | 1.0 |
| VariableReferenceList |
S0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MT_IMS:OG | -1 |
S1 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:Mal | -1 |
P0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MT_IMS:Mal | 1 |
P1 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:OG | 1 |
C0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MT_IM:OGC | 0 |
RapidEquilibriumRandomBiBiProcess
DIC
|
| ID | DIC |
| Name | Dicarboxylate Carrier |
| KiS1 | 0.20E-3 |
| KiS2 | 0.72E-3 |
| KiP1 | 9.0E-4 |
| KiP2 | 7.6E-4 |
| KcF | 2.7 |
| KcR | 4.1 |
| alpha | 1.0 |
| beta | 1.0 |
| gamma | 1.0 |
| delta | 1.0 |
| VariableReferenceList |
S0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MT_IMS:Mal | -1 |
S1 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:Pi | -1 |
P0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MT_IMS:Pi | 1 |
P1 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:Mal | 1 |
C0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MT_IM:DIC | 0 |
RapidEquilibriumRandomBiBiProcess
CIC
|
| ID | CIC |
| Name | Tricarboxylate Carrier |
| KiS1 | 1.3E-4 |
| KiS2 | 4.4E-4 |
| KiP1 | 3.3E-4 |
| KiP2 | 4.18E-5 |
| KcF | 5.6 |
| KcR | 3.5 |
| alpha | 1.0 |
| beta | 1.0 |
| gamma | 1.0 |
| delta | 1.0 |
| VariableReferenceList |
S0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MT_IMS:Cit | -1 |
S1 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:Mal | -1 |
P0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MT_IMS:Mal | 1 |
P1 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:Cit | 1 |
C0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MT_IM:CIC | 0 |
PingPongBiBiProcess
SDH
|
| ID | SDH |
| Name | Succinate Dehydrogenase |
| KmS1 | 30e-6 |
| KmS2 | 0.3e-6 |
| KmP1 | 69E-6 |
| KmP2 | 1.5e-6 |
| KiS1 | 4.1E-6 |
| KiP2 | 5.6E-6 |
| Keq | 1.8E4 |
| KcF | 69.3 |
| KcR | 1.73 |
| VariableReferenceList |
S0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:Suc | -1 |
S1 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MT_IMS:Q | -1 |
P0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:Fum | 1 |
P1 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MT_IMS:QH2 | 1 |
C0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MT_IM:SDH | 0 |
PingPongBiBiProcess
CAC
|
| ID | CAC |
| Name | carnitine Carrier |
| KmS1 | 0.6E-3 |
| KmS2 | 9.4E-3 |
| KmP1 | 43.4E-6 |
| KmP2 | 0.4E-3 |
| KiS1 | 8.7E-6 |
| KiP2 | 250E-6 |
| Keq | 243.3 |
| KcF | 1.22 |
| KcR | 1.08 |
| VariableReferenceList |
S0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MT_IMS:PalCar | -1 |
S1 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:Car | -1 |
P0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:PalCar | 1 |
P1 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MT_IMS:Car | 1 |
C0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MT_IM:CAC | 0 |
OrderedBiBiProcess
CPT_II
|
| ID | CPT_II |
| Name | CPT II |
| KmS1 | 6.3E-4 |
| KmS2 | 3.3E-4 |
| KmP1 | 950E-6 |
| KmP2 | 34E-6 |
| KiS1 | 2.4E-4 |
| KiS2 | 2.7E-4 |
| KiP1 | 41E-6 |
| KiP2 | 7E-6 |
| Keq | 23540 |
| KcF | 8.0 |
| KcR | 2.4 |
| VariableReferenceList |
S0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:PalCar | -1 |
S1 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:CoA | -1 |
P0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:Car | 1 |
P1 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:c16Acyl_CoA | 1 |
C0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MT_IM:CPT_II | 0 |
PingPongBiBiProcess
ETF_QO
|
| ID | ETF_QO |
| Name | ETF-Q oxidoreductase |
| KmS1 | 0.31E-6 |
| KmS2 | 0.39E-6 |
| KmP1 | 0.32E-6 |
| KmP2 | 4.2E-9 |
| KiS1 | 0.31E-6 |
| KiP2 | 0.3E-6 |
| Keq | 0.66 |
| KcF | 78 |
| KcR | 101 |
| VariableReferenceList |
S0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:ETFred | -1 |
S1 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MT_IMS:Q | -1 |
P0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:ETFox | 1 |
P1 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MT_IMS:QH2 | 1 |
C0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MT_IM:ETF_QO | 0 |
OrderedBiBiProcess
ACDa
|
| ID | ACDa |
| Name | Acyl-CoA dehydrogenase |
| KmS1 | 39E-6 |
| KmS2 | 0.12E-6 |
| KmP1 | 1.08E-6 |
| KmP2 | 2.42E-5 |
| KiS1 | 76E-6 |
| KiS2 | 0.24E-6 |
| KiP1 | 7.53E-5 |
| KiP2 | 1.19E-5 |
| Keq | 8.99 |
| KcF | 2.18 |
| KcR | 0.30 |
| VariableReferenceList |
S0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:c16Acyl_CoA | -1 |
S1 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:ETFox | -1 |
P0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:ETFred | 1 |
P1 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:c16Enoyl_CoA | 1 |
C0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MT_IM:ACD | 0 |
MichaelisUniUniReversible1Process
ECHa
|
| ID | ECHa |
| Name | Enoyl-CoA hydratase |
| Ks | 16.9e-6 |
| Kp | 12.1e-6 |
| KcF | 8.9166667 |
| KcR | 2154.1667 |
| VariableReferenceList |
S0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:c16Enoyl_CoA | -1 |
P0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:c16Hydroxyacyl_CoA | 1 |
C0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MT_IM:ECH | 0 |
MichaelisUniUni1Process
HCDa
|
| ID | HCDa |
| Name | 3-Hydroxyacyl-CoA dehydrotgenase |
| Ks | 1.5e-6 |
| KcF | 41.483333 |
| VariableReferenceList |
S0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:c16Hydroxyacyl_CoA | -1 |
P0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MATRIX:c16Oxoacyl_CoA | 1 |
C0 |
Variable:/CELL/CYTOPLASM/MITOCHONDRION/MT_IM:HCD |
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